You are referring to the JS function below found in webwb • pega_desktop_api • js - the one that ends with pega.desktop.openUrlInWindow() ?

You want it, instead, to open in the browser replacing the current page -- not in a popup/modal window -- is this what you are asking?

Why are you using the JS API and not an OOTB control such as a Link, Button, or Icon with a click action configured to open the work item?

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pega.desktop.openWorkItem = function(strItemId, workpool,contentID,dynamicContainerID) {
     var args = arguments[0];
    if (typeof args == "object" && args.name == "safeURL") {
  var oSafeURL = SafeURL_clone(args);
  var strItemId = oSafeURL.get("ID");
  var workpool = oSafeURL.get("workpool");
    } 

    var harnessVersion;
    if (workpool == 0 || workpool == 1){
  harnessVersion= workpool+"";
    }

    var sourceString= "";

    if (!oSafeURL) {
  var oSafeURL= new SafeURL();
    }

   
    if (strItemId && strItemId != "") {
        oSafeURL.put("param", strItemId);
    }
    if (harnessVersion  && harnessVersion != "" ) {
        oSafeURL.put("version", harnessVersion);
    }
    if (contentID && contentID != "" ) {
        oSafeURL.put("contentID", contentID);
    }
    if (dynamicContainerID && dynamicContainerID!= "" ) {
        oSafeURL.put("dynamicContainerID", dynamicContainerID);
    }
    if (workpool && workpool != 1 && workpool != 0) {
        oSafeURL.put("workpool",workpool);
    }

    if (!openSpace("Work", oSafeURL , "openbyworkItem") ) {
        sourceString= oSafeURL.toQueryString();
        var strURL= pega.desktop.support.constructUrl(sourceString , "openbyworkItem");
        pega.desktop.openUrlInWindow(strURL, "pyWorkPage", WorkFormSize + PopupWindowFeatures);
    }
}